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. Author manuscript; available in PMC: 2010 Jan 15.
Published in final edited form as: Glia. 2009 Jan 15;57(2):194–206. doi: 10.1002/glia.20746

Figure 1.

Figure 1

OL progenitors express opioid receptors. A and B. Real time RT-PCR detection of mRNA for MOR, DOR and KOR in (A) striatum and cerebral cortex from embryonic day 15 (E15) mice, and in (B) progenitor cells (PC) from E15 cortex after 2 and 5 days in culture. C and D. Progenitors in E15 cortical cultures stained for MOR (red) and Olig-2 (green), a transcription factor indicating commitment to the OL lineage in these cultures. Arrows indicate double-labeled cells, many of which are Olig-2-, showing that MORs are expressed in both committed and multipotential cells.