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. Author manuscript; available in PMC: 2009 Sep 14.
Published in final edited form as: DNA Repair (Amst). 2007 Mar 26;6(6):830–840. doi: 10.1016/j.dnarep.2007.01.013

Fig. 2. Effect of p53 knockdown on cellular exonuclease activity.

Fig. 2

(A) The EcoRV-linearized (upper) or EcoRI-linearized (lower) plasmids were incubated with 30 μg of extracts for indicated min. As controls, the DNA substrates were incubated without cell extract or with 50 U of exonuclease III. (B) Quantitative expression of exonuclease activity. The intensity determined by Scion imaging (Scion Corporation, Frederick, MD) of unincubated DNA substrate (no extract) was used as control (100%). (C) Quantitative expression of exonuclease activity. The EcoRI-linearized plasmids were incubated without cell extract or with 30 μg of extracts for indicated min. (D) Quantitative expression of exonuclease activity of NHOK.