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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Cell Microbiol. 2009 Apr 30;11(9):1306–1328. doi: 10.1111/j.1462-5822.2009.01332.x

Table 1.

Morphological changes induced on Caco-2 cells by C. perfringens strains.

Strain Time (h) Cytotoxicity*
CN3685 1.5
2 +
2.5 ++
3 +++
CPJV47 1.5
2
2.5 +
3 +
CPJV47(pJVRS3) 1.5
2 +
2.5 ++
3 +++
JGS1495 1.5
2
2.5
3
3.5 +
4 ++
5 +++
CN5383 1.5
2
2.5
3
3.5 +
4 ++
5 +++
*

(+) >80% of Caco-2 cells were swollen, (++) <50% of Caco-2 cells were swollen and <50% of cells were rounded and (+++) >80% of Caco-2 cells were rounded and detached from the glass.