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Top panels show plots of right ventricular pressure versus area for the patch regions of a representative 0-, 2-, and 8-week ECM patch. Area at end diastole is normalized to one. The loops at 8 weeks progressed in a counterclockwise direction and indicated greater RSW relative to 2 and 0 weeks as can be seen by the larger area within the 8-week loop. The bottom panel shows a chart of mean SC and RSW values for the all the dogs in the 0-, 2-, and 8-week groups (*p ≤ 0.05 vs. 0 week).
