Table 3.

Urinary biomarker test characteristics based on optimal cut-off value for the 2-hour post-CPB t point for detection of AKI

Predictor variable	Optimal cut-off point *	Sensitivity (%)	Specificity (%)	Positive predictive value (%)	Negative predictive value (%)
KIM-1 (ng/mg)	0.42	92	58	24	98
NAG (mU/mg)	66	50	79	26	91
NGAL (ng/mg)	166	67	11	15	90
IL-18 (pg/mg)	92	75	66	25	95
Cystatin C (ng/mg)	192	42	86	31	91
α-1 microglobulin (μg/mg)	115	75	58	21	94

^*The optimal cut-off point value was generated using the Youden index; CPB denotes cardiopulmonary bypass