Table 4.

Association of 2-hour post-CPB urinary biomarker level with development of AKI

Predictor variable	OR	95% CI	P value
Unadjusted
KIM-1	1.96	1.26, 3.05	0.003
NAG	1.40	0.96, 2.06	0.08
NGAL	1.01	0.87, 1.16	0.93
IL-18	1.38	1.02, 1.88	0.04
Cystatin C	1.02	0.75, 1.39	0.88
α-1 microglobulin	1.33	0.88, 2.01	0.17
Adjusted for preoperative CCF score
KIM-1	1.69	1.10, 2.59	0.02
NAG	1.25	0.83 1.90	0.29
IL-18	1.29	0.92, 1.82	0.14
Adjusted for intraoperative CPB perfusion time
KIM-1	1.86	1.20, 2.89	0.006
NAG	1.27	0.84, 1.91	0.25
IL-18	1.28	0.91, 1.78	0.15

Logistic regression models were generated to indicate odds ratios per doubling in the urinary biomarker level; OR denotes odds ratio; CI confidence interval; CPB, cardiopulmonary bypass; and CCF, Cleveland Clinic Foundation.