Table 1. Invasion is inhibited in the presence of kinase inhibitors.

Inhibitor	Inhibition for wt1 (%)	Inhibition for H1-2 (%)
LY294002	70.4	48.5
PD98059	50.0	35.4
SB203580	12.8	23.8

Cells were incubated with inhibitors for 1 h before the start of invasion assays. The phosphatidylinositol 3-kinase (PI-3K) inhibitor, LY294002, and the MEK1 inhibitor, PD98059, were used at a concentration of 50 μM, whereas the p38 MAP kinase inhibitor, SB203580, was used at a concentration of 10 μM. Invasion level was determined following 24 h of incubation in the presence of SDF-1-α. Per cent inhibition=per cent invasion in the absence of inhibitor−per cent invasion in the presence of inhibitor/per cent invasion in the absence of inhibitor. Data depicted are representative of two separate experiments.