Table 2. Clinical response according to molecular features.

	Patients		Clinical response a
Marker	n	%	Odds ratio	95% CI	P
TP53 mutation
Absent	72	63	1.00
Present	43	37	1.67	0.74–3.73	0.2
Kras mutation
Absent	80	68	1.00
Present	37	32	1.21	0.54–2.73	0.6
MSI
Absent	114	98	1.00
Present	2	2	0.79	0.05–12.97	0.9
MTHFR 677
CC	43	37	1.00
CT	54	47	0.42	0.18–0.99	0.05
TT	19	16	0.67	0.20–2.17	0.5
CT and TT	73	63	0.47	0.21–1.06	0.07
ERCC1-118
CC	10	9	1.00
CT	64	56	0.35	0.06–1.86	0.2
TT	41	35	0.51	0.09–2.88	0.4
CT and TT	105	91	0.40	0.08–2.10	0.3
XRCC1-399
GG	39	34	1.00
AG	61	53	1.00	0.43–2.34	1.0
AA	15	13	1.28	0.35–4.68	0.7
AG and AA	76	66	1.05	0.46–2.37	0.9

^aComplete response/partial response vs stable disease/progressive disease.