Table 4. Disease-free and overall survivals in the total entire population and subgroups.
Disease-free survival
|
Overall survival
|
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
No.
|
Median (months)
|
Median (months)
|
||||||||
GEM | Surgery-only | GEM | Surgery-only | HR (95% CI) | P-value | GEM | Surgery-only | HR (95% CI) | P-value | |
All patients | 58 | 60 | 11.4 | 5.0 | 0.60 (0.40–0.89) | 0.01 | 22.3 | 18.4 | 0.77 (0.51–1.14) | 0.19 |
R0 | 47 | 52 | 11.4 | 5.1 | 0.58 (0.37–0.91) | 0.02 | 26.8 | 19.1 | 0.70 (0.45–1.09) | 0.11 |
R1 | 11 | 8 | 9.5 | 3.4 | 0.39 (0.15–1.06) | 0.05 | 18.3 | 17.6 | 1.05 (0.41–2.72) | 0.92 |
N0 | 19 | 18 | — | 9.0 | 0.38 (0.16–0.86) | 0.02 | 32.0 | 28.4 | 0.63 (0.29–1.37) | 0.24 |
N1 | 39 | 42 | 8.6 | 4.5 | 0.73 (0.46–1.16) | 0.19 | 17.1 | 17.3 | 0.84 (0.53–1.34) | 0.84 |
Stage I–II | 13 | 14 | — | 10.0 | 0.27 (0.08–0.85) | 0.02 | 67.8 | — | 0.42 (0.15–1.22) | 0.10 |
Stage III–IV | 45 | 46 | 8.9 | 4.6 | 0.68 (0.44–1.05) | 0.08 | 18.3 | 16.3 | 0.82 (0.53–1.26) | 0.36 |
Abbreviations: CI=confidence interval; GEM=gemcitabine; HR=hazard ratio.