Table 4. Relative mean difference (%) between the diagnostic groups for intact suPAR and intact+cleaved suPAR.
Marker | Groups | Relative mean difference and (95% confidence limits in %) | P-value |
---|---|---|---|
suPAR(I–III) | Non-malignant vs No | −3.3 (−13.3–5.8) | 0.488 |
P=0.002a | Adenoma vs no finding | 6.4 (−3.4–17.2) | 0.208 |
Adenoma vs ONM finding | 9.9 (−0.1–21.0) | 0.052 | |
CRC vs adenoma | 9.0 (−1.5–18.5) | 0.089 | |
CRC vs no finding | 17.0 (5.5–29.7) | 0.003 | |
CRC vs ONM finding | 20.9 (10.2–32.6) | <0.0001 | |
suPAR(I–III)+(II–III) | Non-malignant vs No | −6.5 (−17.0–3.1) | 0.190 |
P=0.004a | Adenoma vs no finding | 2.3 (−7.2–12.7) | 0.653 |
Adenoma vs ONM finding | 8.9 (−0.8–19.5) | 0.072 | |
CRC vs adenoma | 8.1 (−1.9–17.2) | 0.110 | |
CRC vs no finding | 11.3 (−0.1–24.0) | 0.052 | |
CRC vs ONM finding | 18.5 (9.0–28.8) | <0.0001 |
Results of type III hypothesis tests (ONM=other non-malignant).