Table 2.
Mild, moderate and severe categories for symptom severity, symptom responses and onset times by trial arm.
| Mild, moderate and severe categories of symptoms | Intervention Arm | Patient Response to Symptom Management | Not included in the analysis of response | Onset time2 | ||||
|---|---|---|---|---|---|---|---|---|
| Response | Non-Response | Remained mild | Not present | Onset on last contact1 | 1st contact | 2nd or later contact | ||
| N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | ||
| Fatigue 0 1, 2−4, 5−10 | NASM | 82 (41.00) | 95 (47.50) | 3 (1.50) | 6 (3.00) | 14 (7.00) | 144 (81.36) | 33 (18.64) |
| ATSM | 95 (51.08) | 63 (33.87) | 10 (5.38) | 8 (4.30) | 10 (5.38) | 148 (93.67) | 10 (6.33) | |
| Weakness 0 1−2, 3−4, 5−10 | NASM | 79 (39.50) | 27 (13.50) | 20 (10.00) | 65 (32.50) | 9 (4.50) | 76 (71.70) | 30 (28.30) |
| ATSM | 61 (33.52) | 32 (17.58) | 38 (20.88) | 43 (23.63) | 8 (4.40) | 70 (75.27) | 23 (24.73) | |
| Depression 0 1, 2−3, 4−10 | NASM | 66 (33.00) | 33 (16.50) | 16 (8.00) | 78 (39.00) | 7 (3.50) | 62 (62.63) | 37 (37.37) |
| ATSM | 69 (37.50) | 17 (9.24) | 19 (10.33) | 67 (36.41) | 12 (6.52) | 68 (79.07) | 18 (20.93) | |
| Difficulty Remembering 0 1, 2−4, 5−10 | NASM | 63 (31.50) | 41 (20.50) | 18 (9.00) | 71 (35.50) | 7 (3.50) | 77 (74.04) | 27 (25.96) |
| ATSM | 46 (25.27) | 30 (16.48) | 24 (13.19) | 73 (40.11) | 9 (4.95) | 60 (78.95) | 16 (21.05) | |
| Pain 0 1, 2−4, 5−10 | NASM | 68 (34.00) | 29 (14.50) | 10 (5.00) | 76 (38.00) | 17 (8.50) | 61 (62.89) | 36 (37.11) |
| ATSM | 45 (32.14) | 36 (25.71) | 21 (15.00) | 30 (21.43) | 8 (5.71) | 58 (71.60) | 23 (28.40) | |
| Insomnia 0 1−3, 4−6, 7−10 | NASM | 64 (32.00) | 22 (11.00) | 52 (26.00) | 53 (26.50) | 9 (4.50) | 63 (73.26) | 23 (26.74) |
| ATSM | 56 (30.77) | 19 (10.44) | 62 (34.07) | 38 (20.88) | 7 (3.85) | 61 (81.33) | 14 (18.67) | |
| Poor Appetite 0 1−3, 4−5, 6−10 | NASM | 69 (34.50) | 19 (9.50) | 27 (13.50) | 74 (37.00) | 11 (5.50) | 51 (57.95) | 37 (42.05) |
| ATSM | 71 (38.38) | 11 (5.95) | 53 (28.65) | 38 (20.54) | 12 (6.49) | 61 (74.39) | 21 (25.61) | |
| Anxiety 0 1−3, 4−5, 6−10 | NASM | 55 (27.50) | 19 (9.50) | 61 (30.50) | 58 (29.00) | 7 (3.50) | 45 (60.81) | 29 (39.19) |
| ATSM | 56 (30.43) | 9 (4.89) | 66 (35.87) | 46 (25.00) | 7 (3.76) | 48 (73.85) | 17 (26.15) | |
| Dyspnea 0 1−2, 3−6, 7−10 | NASM | 38 (19.00) | 24 (12.00) | 25 (12.50) | 108 (54.00) | 5 (2.50) | 37 (59.68) | 25 (40.32) |
| ATSM | 43 (23.12) | 18 (9.68) | 32 (17.20) | 79 (43.41) | 10 (5.49) | 41 (67.21) | 20 (32.79) | |
| Dry Mouth 0 1−4, 5−8, 9−10 | NASM | 52 (26.00) | 9 (4.50) | 81 (40.50) | 52 (26.00) | 6 (3.00) | 34 (55.74) | 27 (44.26) |
| ATSM | 38 (20.88) | 8 (4.40) | 62 (34.07) | 70 (38.46) | 4 (2.20) | 28 (60.87) | 18 (39.13) | |
| Constipation 0 1−3, 4−6, 7−10 | NASM | 36 (18.00) | 10 (5.00) | 35 (17.50) | 113 (56.50) | 6 (3.00) | 29 (63.04) | 17 (36.96) |
| ATSM | 52 (28.26) | 9 (4.89) | 55 (29.89) | 60 (32.61) | 8 (4.35) | 46 (75.41) | 15 (24.59) | |
| Cough 0 1−2, 3−4, 5−10 | NASM | 37 (18.50) | 20 (10.00) | 35 (17.50) | 103 (51.50) | 5 (2.50) | 37 (64.91) | 20 (35.09) |
| ATSM | 45 (24.46) | 4 (2.17) | 46 (25.00) | 82 (44.57) | 7 (3.80) | 30 (61.22) | 19 (38.78) | |
| Peripheral Neuropathy 0 1−3, 4−7, 8−10 | NASM | 23 (11.50) | 24 (12.00) | 43 (21.50) | 103 (51.50) | 7 (3.50) | 28 (59.57) | 19 (40.43) |
| ATSM | 40 (21.98) | 14 (7.69) | 55 (30.22) | 66 (36.26) | 7 (3.85) | 28 (51.85) | 26 (48.15) | |
| Nausea/Vomiting 0 1−3, 4−6, 7−10 | NASM | 36 (18.00) | 5 (2.50) | 39 (19.50) | 114 (57.00) | 6 (3.00) | 19 (46.34) | 22 (53.66) |
| ATSM | 38 (20.88) | 12 (8.79) | 51 (28.02) | 76 (41.76) | 5 (2.75) | 33 (66.00) | 17 (34.00) | |
| Diarrhea 0 1−3, 4−5, 6−10 | NASM | 27 (13.50) | 5 (2.50) | 31 (15.50) | 132 (66.00) | 5 (2.50) | 12 (37.50) | 20 (62.50) |
| ATSM | 23 (12.57) | 6 (3.28) | 64 (34.97) | 87 (47.54) | 3 (1.64) | 17 (58.62) | 12 (41.38) | |
Onset on last contact1: Symptom reached moderate or severe for the first time at the last contact, no follow-up contact.
Onset Time2: Intervention contact when symptom reached moderate or severe level for the first time.