Figure 4. The IL-6 response to CLP is reduced in GM-CSF deficient mice.

Wild type (WT) or GM-CSF^−/− (KO) mice were subjected to the CLP procedure (n=8/group) or sham surgery (4/group) and the TNF-α levels were quantified in peritoneal fluid (PF) or serum after 6 hr (A), or 24 hr (B). For statistical comparisons between corresponding values for GM-CSF and wild type mice, p values of <0.01 (*) and <0.001 (**) are indicated.