TABLE 3.

Dose-response effect of interpregnancy weight gain among women with gestational diabetes who gained more than 10 pounds on the risk of cesarean delivery during the subsequent pregnancy

	Number of Deliveries			Odds Ratios of Cesarean Delivery at Subsequent Birth
Weight Gain (lbs)	Total	Vaginal (%)	Cesarean (%)	OR1	95% CI	Adjusted OR2,3	95% CI
Weight stable (±10)	1394	94.8	5.2	1.0		1.0
11-16	278	92.4	7.6	1.48	0.89-2.45	1.48	0.86-2.52
17-27	325	90.5	9.5	1.91	1.23-2.96	1.76	1.06-2.93
Greater than 27	303	88.4	11.6	2.36	1.55-3.61	2.36	1.37-4.06

¹Unadjusted

²Adjusted for mother’s age, mother’s education, mother’s race/ethnicity, mother’s smoking during the subsequent pregnancy, pre-pregnancy weight of the baseline pregnancy, weight gain during the baseline and subsequent pregnancy, interbirth interval, year of birth (subsequent pregnancy)

³P = 0.001 for test for trend by multivariate logistic regression in which the main exposure, weight gain, was categorized as an ordinal variable. p=0.004 for test for trend by multivariate logistic regression in which the main exposure, weight gain, was categorized as a continuous variable.