Table 2.
Odds ratio for the risk of hip fracture
| Vitamin D* | Unadjusted | MV-adj† |
|---|---|---|
| Number of missing pairs (total =400) | 18** | y18** |
| Per 2.5 nM (1 ng/ml) decrease‡ | 1.03 (1.01, 1.05) | 1.03 (1.01, 1.05) |
| Per 25 nM (10 ng/ml) decrease | 1.30 (1.07, 1.58) | 1.33 (1.06, 1.68) |
| p for linear trend | p = 0.009 | p = 0.015 |
| Quartiles (according to control group) | ||
| 1st Quartile (<47.6 nM) | 1.73 (1.13, 2.66) | 1.71 (1.05, 2.79) |
| 2nd Quartile (47.6− <60.2 nM) | 1.08 (0.72, 1.63) | 1.09 (0.70, 1.71) |
| 3rd Quartile (60.2−<70.7 nM) | 0.78 (0.50, 1.20) | 0.82 (0.51, 1.31) |
| 4th Quartile (70.7+ nM) (ref) | 1 (ref) | 1 (ref) |
Hip fractures case and controls selection matched on age, ethnicity and blood draw date.
Because of deletion of cases and controls due to missing values, 18 case-control pairs were missing from our multivariable models. We also excluded these pairs from our unadjusted models to ensure the same analytic sample.
Multivariate adjustment includes age, body mass index, parental history of hip fracture, history of fracture, smoking, alcohol use, and total calcium intake, oral corticosteroid use and geographic region.
To convert values for 25-hydroxyvitamin D to ng/ml divide by 2.5.