Table 2.

Single SNP analysis of TNFSF13B SNPs and risk of NHL and NHL subtypes

					ALL NHL (n=441)		CLL/SLL (n=123)		Follicular NHL (n= 113)		DLBCL (n=69)
SNP	Position (bp)	Gene region	Major/Minor Alleles	MAF control	OR (95% CI)	P-value	OR (95% CI)	P-value	OR (95% CI)	P-value	OR (95% CI)	P-value
rs9514828	107719374	promoter	C/T	0.49	1.01 (0.84, 1.21)	0.93	1.08 (0.82, 1.43)	0.57	1.00 (0.75, 1.34)	0.99	0.99 (0.70, 1.40)	0.95
rs8181791	107732046	intron	A/G	0.37	0.91 (0.75, 1.10)	0.34	1.06 (0.78, 1.43)	0.71	1.01 (0.74, 1.37)	0.96	0.79 (0.54, 1.17)	0.24
rs1224141	107733724	intron	T/G	0.234	0.77 (0.61, 0.97)	0.03	0.82 (0.57, 1.18)	0.28	0.81 (0.56, 1.16)	0.25	0.78 (0.49, 1.24)	0.29
rs12583006	107735453	intron	T/A	0.25	0.75 (0.60, 0.94)	0.01	0.86 (0.61, 1.21)	0.39	0.80 (0.55, 1.14)	0.22	0.65 (0.41, 1.04)	0.07
rs12428930	107737706	intron	A/C	0.25	0.75 (0.60, 0.94)	0.01	0.88 (0.63, 1.24)	0.48	0.79 (0.55, 1.14)	0.20	0.65 (0.40, 1.04)	0.07
rs10508198	107740789	intron	G/C	0.30	1.21 (0.99, 1.47)	0.06	0.97 (0.71, 1.33)	0.85	1.19 (0.88, 1.62)	0.25	1.39 (0.96, 2.03)	0.08
rs1224147	107754759	intron	T/C	0.234	1.18 (0.96, 1.46)	0.12	0.88 (0.62, 1.25)	0.47	1.20 (0.87, 1.67)	0.27	1.13 (0.74, 1.71)	0.58
rs9520836	107755064	intron	A/G	0.26	1.01 (0.82, 1.25)	0.91	1.03 (0.75, 1.42)	0.86	1.01 (0.72, 1.42)	0.94	1.02 (0.67, 1.53)	0.94
rs7982100	107756366	intron	C/T	0.007	1.94 (0.77, 4.93)	0.16	2.12 (0.60, 7.41)	0.24	1.76 (0.45, 6.94)	0.42	1.02 (0.12, 8.47)	0.99

*Odds ratio and 95% confidence interval assuming log-additive genetic model adjusted for gender, and age.