Table 3.
BMI category and physiologic and clinical characteristics of asthma.
| Variable | BMI < 25* | BMI ≥ 25* | Crude p | Adjusted p* |
|---|---|---|---|---|
| FEV1 (L, prebronchodilator) (n=593/671) | 3.05 [2.98, 3.11] | 2.91 [2.85, 2.97] | 0.0001 | 0.001 |
| FEV1 (%, prebronchodilator) (n=593/671) | 83.5 [82.5, 84.5] | 82.4 [81.5, 83.4] | 0.03 | 0.1 |
| FEV1/FVC (%)(n=593/671) | 72.6 [71.8, 73.4] | 71.3 [70.6, 72.1] | 0.01 | 0.01 |
| Morning peak expiratory flow (L/min) (n=592/671) | 437.4 [427.6, 447.2] | 443.7 [434.4, 453.0] | 0.5 | 0.3 |
| Daily rescue albuterol use (puffs) (n=590/669) | 1.08 [0.98, 1.18] | 1.2 [1.1, 1.3] | 0.05 | 0.03 |
| PC20 methacholine (mg/mL) (n=531/591) | 1.0 [0.86, 1.16] | 1.07 [0.93, 1.24] | 0.1 | 0.4 |
| Exhaled nitric oxide (ppb) (n=300/371) | 16.0 [14.5, 17.6] | 14.9 [13.6, 16.3] | 0.1 | 0.2 |
| Total number of positive skin tests (n=523/604) | 5.23 [4.94, 5.51] | 5.28 [5.01, 5.55] | 0.7 | 0.8 |
| Asthma-related quality of life (n=492/567) | 5.77 [5.69, 5.85] | 5.59 [5.52, 5.67] | 0.001 | 0.0004 |
| Mini-ACQ score (n=206/269) | 1.09 [1.0, 1.19] | 1.09 [1.0, 1.18] | 0.7 | 1.0 |
n reported for BMI <25/BMI ≥ 25.
Means and p values after adjustment for study, age, gender and race. ACQ = Asthma Control Questionnaire. Data presented as mean and [95% CI].