Table 4.
BMI category and physiologic and clinical characteristics of asthma.
| Variable | BMI < 25* | BMI ≥ 30* | Crude p | Adjusted p* |
|---|---|---|---|---|
| FEV1 (L, prebronchodilator) (n=593/279) | 3.05 [2.98, 3.11] | 2.78 [2.69, 2.86] | <0.0001 | <0.0001 |
| FEV1 (%, prebronchodilator) (n=593/279) | 83.5 [82.4, 84.5] | 81.4 [80.0, 82.8] | 0.0003 | 0.01 |
| FEV1/FVC (%)(n=593/279) | 72.7 [71.8, 73.5] | 72.2 [71.0, 73.4] | 0.3 | 0.5 |
| Morning peak expiratory flow (L/min) (n=592/278) | 436.6 [426.6, 446.5] | 432.0 [418.4, 445.6] | 0.2 | 0.6 |
| Daily rescue albuterol use (puffs) (n=590/277) | 1.08 [0.98, 1.19] | 1.27 [1.13, 1.43] | 0.06 | 0.01 |
| PC20 methacholine (mg/mL) (n=531/251) | 0.98 [0.83, 1.15] | 1.23 [1.01, 1.5] | 0.01 | 0.03 |
| Exhaled nitric oxide (ppb) (n=300/163) | 16.3 [14.7, 18.2] | 13.8 [12.2, 15.7] | 0.02 | 0.02 |
| Total number of positive skin tests (n=523/258) | 5.23 [4.94, 5.52] | 5.48 [5.09, 5.86] | 0.2 | 0.3 |
| Asthma-related quality of life (n=492/234) | 5.75 [5.67, 5.84] | 5.46 [5.35, 5.57] | <0.0001 | <0.0001 |
| Mini-ACQ score (n=206/125) | 1.11 [1.01, 1.22] | 1.12 [0.99, 1.25] | 0.5 | 0.9 |
n reported for BMI<25/BMI≥30.
Means and p values after adjustment for study, age, gender and race.
ACQ = Asthma Control Questionnaire.