Table 2.
Sensitivity, specificity, positive predictive value and negative predictive value for selected cutoffs for the urine protein–creatinine ratio and the urinalysis for predicting ≥300 mg protein per 24 h urine
| Test result | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|
| UPCR | ||||
| ≥0.15a | 96 | 53 | 66 | 94 |
| ≥0.17 | 91 | 58 | 67 | 88 |
| ≥0.19 | 89 | 70 | 74 | 88 |
| ≥0.24 | 73 | 87 | 84 | 78 |
| ≥0.28 | 66 | 95 | 93 | 75 |
| ≥0.39 | 55 | 100 | 100 | 71 |
| UA | ||||
| ≥Negative | 100 | 0 | 48 | –b |
| ≥1+ | 41 | 100 | 100 | 65 |
| ≥2+ | 23 | 100 | 100 | 58 |
| ≥3+ | 11 | 100 | 100 | 55 |
Abbreviations: UA, urinalysis; UPCR, urine protein–creatinine ratio.
Using a cutoff of ≥0.15, two subjects with significant 24-h proteinuria (304 and 336 mg) were missed.
This number could not be calculated due to 0 in the denominator.