. Author manuscript; available in PMC: 2009 Sep 14.

Published in final edited form as: Neuropsychopharmacology. 2007 May 16;33(4):837–848. doi: 10.1038/sj.npp.1301456

Table 6.

GABRA2 6-SNP haplotype (snps 7, A-E; rs1440133, 567926, 534459, 529826, 279869, 279858) frequencies for self-identified EA and AA subjects.

	EA -Connecticut sample			EA - Project Match		AA Subjects			EA c/w AA controls
Haplotype^*	Controls (n=535)	AD (n=372)	^aχ²; p-value	AD (n=727)	^bχ²; p-value	Controls (n=100)	AD (n=148)	^cχ²; p-value	^dχ²; p-value
GAGTGT	.585	.524	6.18; .013	.561	1.94; .16	.281	.278	0.00; .95	60.50; <.001
AGACTC	.386	.432	3.78; .052	.414	1.63; .20	.229	.228	0.00; .98	17.13; <.001
GAACTT	.005	.001	N/A	.001	N/A	.453	.440	0.16; .69	469.8; <.001

Only those haplotypes with frequency >0.05 in at least one subgroup are shown.

2X2 χ² table (haplotype (y) vs. all others) EA Controls compared with EA Connecticut Alcoholics

EA Controls compared with EA MATCH Alcoholics

AA Controls compared with AA Alcoholics (Connecticut and MATCH combined)

EA Controls compared with AA Controls

N/A–χ² table cell expected counts <5