Table 4.
Summary of new grouping scheme
Group | AML | MDS or AML arising from MDS |
---|---|---|
Favorable | t(8;21) alone inv(16)/t(16;16)/del(16q22) with M4 t(15;17) |
|
Standard-risk | Normal del(9q) t(8;21) + del(9q) or complex Trisomy 8 Abnormal 5 or 7 Abnormal 11q23 All others |
Normal Abnormal 3q Abnormal 5 Trisomy 8 All others |
Adverse | Complex t(9;22) t(6;9) |
Abnormal 7 Complex |
Patients with AML and abnormal 3q, as well as patients with MDS and 5q-, 20q-, or Y- are not classified in this analysis, as too few patients with those abnormalities were present in our cohort to assign to a risk group