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. Author manuscript; available in PMC: 2009 Sep 14.
Published in final edited form as: Acta Neurochir Suppl. 2008;104:287–290. doi: 10.1007/978-3-211-75718-5_59

Fig. 1.

Fig. 1

Proposed pathways of protection against cerebral vasospasm by statins. eNOS Endothelial nitric oxide synthase; NADPH oxidase nicotinamide adenine dinucleotide phosphate oxidase; NO nitric oxide; PI3K phosphatidyl-inositol-3 kinase; RhoK Rho kinase; ROS reactive oxygen species; ↑ upregulation; ↓ inhibition or down-regulation; *proposed targets of statins