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(A–C) CD spectra of the unmodified duplex (—), the C8-IQ-modified single strand (---), and the C8-IQ-modified duplex (---) oligonucleotides at positions G1 (2a, panel A), G2 (3a, panel B), and G3 (4a, panel C) of the NarI restriction sequence. (D–F) UV spectra of the C8-modified single strand (---) and double strand (—) oligonucleotides at positions G1 (2a, panel D), G2 (3a, panel E), and G3 (4a, panel F) of the NarI restriction sequence.
