Table 1.
Association of SCGB3A2 With Clinicopathological Variables
| Variables | Negative (%) | Positive (%) |
Total | P value | |||
|---|---|---|---|---|---|---|---|
| (−) | (+) | (2+) | total (+, 2+) | ||||
| Age | < Median | 27 (28.7) | 39 (41.5) | 28 (29.8) | 67 (71.3) | 94 | 0.340 |
| ≤ Median | 13 (21.0) | 24 (38.7) | 25 (40.3) | 49 (79.0) | 62 | ||
| Sex | Male | 31 (31.0) | 39 (39.0) | 30 (30.0) | 69 (69.0) | 100 | 0.100 |
| Female | 9 (16.1) | 24 (42.9) | 23 (41.1) | 47 (83.9) | 56 | ||
| Histology* | Ad | 13 (13.5) | 40 (41.7) | 43 (44.8) | 83 (86.5) | 96 | <0.001 |
| Sq | 22 (50.0) | 18 (40.9) | 4 (9.1) | 22 (50.0) | 44 | ||
| LC | 1 (11.1) | 3 (33.3) | 5 (55.6) | 8 (88.9) | 9 | ||
| SCLC | 4 (57.1) | 2 (28.6) | 1 (14.3) | 3 (42.9) | 7 | ||
| Differentiation† | Well | 7 (12.5) | 21 (37.5) | 28 (50.0) | 49 (87.5) | 56 | 0.720 |
| Moderately | 5 (14.7) | 17 (50.0) | 12 (35.3) | 29 (85.3) | 34 | ||
| Poor | 1 (16.7) | 2 (33.3) | 3 (50.0) | 5 (83.3) | 6 | ||
| Subtype‡ | Pap | 6 (9.1) | 26 (39.4) | 34 (51.5) | 60 (90.9) | 66 | 0.040 |
| Tub | 5 (38.5) | 4 (30.8) | 4 (30.8) | 8 (61.5) | 13 | ||
| BAC | 2 (12.5) | 9 (56.3) | 5 (31.3) | 14 (87.5) | 16 | ||
| Morphology§ | Clara + typeII | 4 (9.5) | 17 (40.5) | 21 (50.0) | 38 (90.5) | 42 | 0.006 |
| Ciliated | 2 (5.3) | 17 (44.7) | 19 (50.0) | 36 (94.7) | 38 | ||
| Goblet | 3 (60.0) | 1 (20.0) | 1 (20.0) | 2 (40.0) | 5 | ||
| Bronchial gland | 4 (36.4) | 5 (45.5) | 2 (18.2) | 7 (63.6) | 11 | ||
| Stage | I, II | 18 (20.7) | 40 (46.0) | 29 (33.3) | 69 (79.3) | 87 | 0.178 |
| III, IV | 22 (33.3) | 23 (34.8) | 21 (31.8) | 44 (66.7) | 66 | ||
| Total | 40 (25.6) | 63 (40.4) | 53 (34.0) | 116 (74.4) | 156 | ||
*
Ad, adenocarcinoma; Sq, squamous cell carcinoma; LC, large cell carcinoma; SCLC, small cell carcinoma.
†
Only adenocarcinomas were included.
‡
Only adenocarcinomas were included. Pap, papillary adenocarcinoma; Tub, tubular adenocarcinoma; BAC, bronchiolo-alveolar carcinoma
Only adenocarcinomas were included.
§
Clara + type II, Clara cell/ type II alveolar epithelial cell type; Ciliated, ciliated epithelial cell type; Goblet, goblet cell type; Bronchial gland, bronchial gland cell type.