Table 6.

Clinical sensitivity and specificity of UGT1A1 genotyping for severe neutropenia

Study	True positive	False negative	True negative	False positive	Sensitivity (%)	Specificity (%)
Carlini 200551	0	2	59	5	0	92
Innocenti 200414	4	5	48	2	44	96
Iyer 200245	2	0	18	2	100	90
Marcuello 200446	4	18	73	6	18	92
Massacesi 200647	1	3	52	6	25	90
Rouits 200448	4	10	59	3	29	95
Soepenberg 200549	0	1	21	1	0	95
Toffoli 200650	4	33	195	18	11	92
Alla (95% confidence interval)					23 (15–34)	92 (90–94)

^aUsing a random effects model.