Table 1.
Clinical information on ALS patients and controls.
| Clinical variables | Patients | Controls |
| Number | ||
| Dataset 1 | 30 | 30 |
| Dataset 2 | 30 | 30 |
| Dataset 3 | 63 | 63 |
| Male gender (%) | ||
| Dataset 1 | 15 (50) | 15 (50) |
| Dataset 2 | 14 (47) | 15 (50) |
| Dataset 3 | 38 (60) | 40 (63) |
| Age at blood collection ¶ | ||
| Dataset 1 | 63.8 (41.0–76.0) | 62.8 (42.8–80.8) |
| Dataset 2 | 63.7 (35.3–79.5) | 64.8 (36.2–75.8) |
| Dataset 3 | 65.0 (23.5–80.8) | 64.1 (36.9–81.2) |
| Age at disease onset ¶ | ||
| Dataset 1 | 62.8 (40.5–75.6) | |
| Dataset 2 | 62.5 (34.2–78.4) | |
| Dataset 3 | 64.4 (21.5–79.6) | |
| Bulbar Onset (%) | ||
| Dataset 1 | 15 (50) | |
| Dataset 2 | 15 (50) | |
| Dataset 3 | 14 (22) |
For the three independent datasets, we report sample sizes and patient characteristics. The close similarity between patients and controls reflects the fact that healthy controls were chosen such that they matched the age and gender of the patients.
¶ Median years (range)