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. Author manuscript; available in PMC: 2009 Sep 14.
Published in final edited form as: J Physiol Pharmacol. 2008 Dec;59(Suppl 8):47–59.

Table 1.

Hemodynamic parameters and renal sympathetic nerve activity in response to ET1 administration into the SFO with and without antagonism of V1a receptors in PVN

MAP mmHg Heart Rate bpm RSNA %baseline
Baseline 130.6 ± 4.1 407 ± 21 100 ± 0
10 min After ET1 (SFO) 146.4 ± 5.4 374 ± 27 96.9 ± 15.8
MAP mmHg Heart Rate bpm RSNA %baseline
Baseline 130.1 ± 4.8 403 ± 14 100 ± 0
After V1aR antagonism (PVN) 131.9 ± 5.8 403 ± 13 91.7 ± 8.2
10 min After ET1 (SFO) 138.0 ± 5.6* 385 ± 15 87.1 ± 7.0

V1aR antagonist, 10 ng; ET1, 5 pmol.

Values are mean ± SE; n = 5

*

P < 0.015 vs ET1 without V1aR antagonism