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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Int J Obes (Lond). 2009 Jun 30;33(9):1013–1022. doi: 10.1038/ijo.2009.129

Figure 3.

Figure 3

Quantitative targeted peptidomics of α-MSH and γ-MSH. Peak areas of the MRM transitions are combined and plotted on a log scale for each mouse. Mice are sorted by genotype with the PREPgt/gt mice on the left side and the wild-type PREPWT/WT mice on the right. Linear correlation between the two endogenous peptides underlines that γ-MSH, which is not a putative PREP substrate, can be used as an endogenous control to normalize α-MSH quantities across biological replicates.