Table 2.
Body composition phenotypes of male and female pups of either wild-type (PREPWT/WT) or heterozygous PREPWT/gt) mothers. Pups were fed LF diet only. Data are means ± SE.
Maternal Genotype | 2-way ANOVA1 | ||||||
---|---|---|---|---|---|---|---|
|
PREPWT/WT
2 |
PREPWT/gt |
PREPWT/WT |
PREPWT/gt |
Maternal genotype |
Gender of pups |
Interaction |
Male pups | Female pups | ||||||
AN length (cm) | 9.9 ± 0.0 a | 10.0 ± 0.0 a | 9.6 ± 0.1 b | 9.6 ± 0.0 b | NS | <0.0001 | NS |
Body Mass Index | 0.28 ± 0.00 b | 0.31 ± 0.00 a | 0.22 ± 0.00 d | 0.25 ± 0.00 c | <0.0001 | <0.0001 | NS |
Liver weight (g) | 0.97 ± 0.02 b | 1.11 ± 0.03 a | 0.88 ± 0.02 c | 1.03 ± 0.03 ab | <0.0001 | 0.0006 | NS |
Kidney weight (g) | 0.30 ± 0.00 b | 0.32 ± 0.01 a | 0.22 ± 0.00 d | 0.24 ± 0.00 c | <0.0001 | <0.0001 | NS |
Spleen weight (g) | 0.07 ± 0.00 b | 0.09 ± 0.00 a | 0.07 ± 0.00 b | 0.08 ± 0.00 a | <0.0001 | NS | NS |
P values were calculated by ANOVA: Bonferroni correction for multiple tests sets significant P value at ≤ 0.001. Post hoc comparisons were by Tukey's HSD: means not sharing a letter are significant at P = 0.05.
Group sizes: Males: PREPWT/WT, N=46; PREPWT/gt, N=42. Females: PREPWT/WT, N=32; PREPWT/gt, N=39.