Table 7.
Effect of NXY-059 on motor impairment and neglect in marmosets (permanent ischaemia)
| Group | n | Coefficient | 95% CI | P-value |
|---|---|---|---|---|
| Motor | ||||
| Baseline | 32 | 0.03 | −0.43 to 0.49 | 0.90 |
| 3 weeks | 32 | 3.20 | 0.12 to 6.29 | 0.04 |
| Males | 17 | 2.54 | −0.58 to 5.67 | 0.11 |
| Females | 15 | 3.17 | −2.05 to 8.40 | 0.24 |
| Neglect | ||||
| Baseline | 32 | 0.004 | −0.003 to 0.01 | 0.24 |
| 3 weeks | 32 | 5.99 | 2.05 to 9.94 | 0.003 |
| Males | 17 | 5.11 | −0.72 to 10.94 | 0.09 |
| Females | 15 | 6.67 | 1.47 to 11.86 | 0.01 |
Analyses based on individual animal data only. Data are coefficients by presence or absence of NXY-059; 95% confidence intervals (95% CI) and significance. Results in bold are statistically significant.
NXY-059, disodium 2,4-disulphophenyl-N-tert-butylnitrone.