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Strontium ranelate increases human osteoblast survival. Cell survival was measured as live cell counts post H2O2-induced oxidative stress after 48-h strontium ranelate treatment (A) or caspase 3/7 was measured with a commercial kit after 6 days' serum deprivation (B). Concentrations are expressed as added to the vehicle, which contains 1 mM Ca2+. ***P < 0.001 compared with vehicle; **P < 0.01 compared with vehicle; *P < 0.05 compared with vehicle.
