Table 3.
Ethanol Preference in Adolescence and Adulthood
Adolescence | Adulthood | ||||
---|---|---|---|---|---|
Acquisition | Two Bottle Choice | Acquisition | Two Bottle Choice | ||
E/N | Male | 38.2 ± 5.4 # | 0.8 ± 0.2 | 21.2 ± 4.3 | 2.3 ± 1.5 |
Female | 44.8 ± 7.5 # | 1.8 ± 0.7 | 27.8 ± 2.3 | 1.0 ± 0.4 | |
Vehicle | Male | 57.6 ± 6.0 *# | 1.1 ± 0.3 | 31.1 ± 5.4 | 2.8 ± 1.0 |
Female | 43.5 ± 5.6 | 4.0 ± 1.8 | 49.7 ± 8.0* | 12.5 ± 4.7* |
Within Group Age Comparison (p ≤ 0.01)
Between Group Comparisons (p≤ 0.05)
Preference was defined as percent total fluid that was ethanol presented as mean ± SEM. During adolescence acquisition, vehicle-treated males had a higher preference compared to E/N males (* p ≤0.05). E/N and vehicle males and E/N females had a greater ethanol preference during the adolescent acquisition phase (# p<.01) than during adulthood. Vehicle-treated females had a higher ethanol preference compared to all groups during adulthood acquisition and two bottle choice phases (* p≤0.05).