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. Author manuscript; available in PMC: 2010 Apr 28.
Published in final edited form as: J Am Coll Cardiol. 2009 Apr 28;53(17):1475–1487. doi: 10.1016/j.jacc.2009.02.007

Table 4.

Overview of the diagnostic accuracy of several combinations of tissue criteria.

T2+LGE Validation Sens Spec Acc PPV NPV
Abdel-Aty et al., J Am Coll Cardiol 2005 (13) Clinical 40% 100% 69% 100% 61%
Gutberlet et al., Radiology 2008 (34) Histology 17% 91% 48% 73% 44%
Pooled data (n=130) 25% 95% 56% 86% 50%
T2 and/or LGE Validation Sens Spec Acc PPV NPV
Abdel-Aty et al., J Am Coll Cardiol 2005 (13) Clinical 88% 74% 81% 100% 85%
Gutberlet et al., Radiology 2008 (34) Histology 50% 57% 52% 80% 25%
Pooled data (n=130) 60% 66% 62% 79% 43%
Any one of three Validation Sens Spec Acc PPV NPV
Abdel-Aty et al., J Am Coll Cardiol 2005 (13) Clinical 100% 48% 75% 68% 100%
Gutberlet et al., Radiology 2008(42) Histology 81% 49% 67% 68% 65%
Pooled data (n=130) 88% 48% 70% 68% 76%
Any two of three Validation Sens Spec Acc PPV NPV
Abdel-Aty et al., J Am Coll Cardiol 2005 (13) Clinical 76% 96% 85% 95% 79%
Gutberlet et al., Radiology 2008 (34) Histology 63% 89% 73% 88% 63%
Pooled data (n=130) 67% 91% 78% 91% 69%

Sens: Sensitivity; Spec: Specificity; Acc: Accuracy; PPV: Positive predictive value; NPV: Negative predictive value