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. Author manuscript; available in PMC: 2009 Sep 15.
Published in final edited form as: Bioconjug Chem. 2006 Nov–Dec;17(6):1545–1550. doi: 10.1021/bc060154p

Figure 4.

Figure 4

Representative ligand binding curves generated through competitive ligand binding analysis compare the binding affinities of ligands 10 (□) and 13 (■). The calculated IC50 for 10 is 8 nM with an R2 value = 0.91 and for 13 10 nM with an R2 value = 0.93.