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Binding of Linked MSH Ligands to hMC4R. State A: L1 is bound, L2 is unavailable for binding. State B: L1and L2 are unbound, L1 is positioned for binding. State C: L1and L2 are unbound, L2 is positioned for binding. State D: L2 is bound, L1 is unavailable for binding. State E: Compound is dissociated from cell surface (not shown).
