Table 1.
IC50 and sensitization ratio of taxol and its combinations with Rosco towards human colorectal cancer cell lines
| Treatment with taxol and combinations with Rosco |
IC50 (mol/L) |
Sensitization ratio1 |
||||
| SW48 | SW1116 | SW837 | SW48 | SW1116 | SW837 | |
| Taxol | 4.8 × 10-8 | 1.2 × 10-7 | 3.8 × 10-7 | - | - | - |
| Taxol + 5 μg/mL Rosco | 7.4 × 10-10 | 1.0 × 10-8 | 5.4 × 10-8 | 65 | 12 | 7 |
| Taxol + 10 μg/mL Rosco | 7.5 × 10-11 | 8.1 × 10-10 | 6.7 × 10-10 | 6.4 × 102 | 1.5 × 102 | 5.7 × 102 |
1
Sensitization ratio = IC50 (taxol)/IC50 (taxol + Rosco).