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. Author manuscript; available in PMC: 2010 Sep 24.
Published in final edited form as: Mol Cell Endocrinol. 2009 Jan 21;308(1-2):63–69. doi: 10.1016/j.mce.2009.01.007

Figure 1. Schematic comparison of TRβ1 and TRβPV structure.

Figure 1

The TRβPV mutation was identified in a patient with resistance to thyroid hormone. The TRβPV mutation is a frameshift mutation due to a C-insertion at codon 448 of TRβ1. The carboxyl-terminal sequences of the wild-type TRβ and the TRβPV mutant are indicated.