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. Author manuscript; available in PMC: 2010 May 14.
Published in final edited form as: J Med Chem. 2009 May 14;52(9):2846–2853. doi: 10.1021/jm801643b

Figure 1. Search for TCCYP51 inhibitors.

Figure 1

(A) Ligands (1–6) found via HTS using FMP library of small organic molecules (20,000-compounds selected from ChemDiv, San Diego, CA); (B) inhibitors (7–11) found using web-database search for structural similarity to 5 (http://chemdiv.emolecules.com); (C) 9-like INDO-amide derivatives. Calculated from spectral responses apparent dissociation constants (μM) for the compounds not included in Table 1 are shown in brackets.