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. Author manuscript; available in PMC: 2009 Sep 15.
Published in final edited form as: J Urol. 2008 Mar;179(3):1178–1183. doi: 10.1016/j.juro.2007.10.030

Fig. 4.

Fig. 4

Effect of intrathecal application of muscimol (white circles; 0.001–0.1 μg) or baclofen (black circles; 0.001–1 μg) on the number (A), maximal (B), and average voltage (C) of EUS-EMG spikes during voiding bladder contractions, compared with the values before injection (control) in SCI rats. A: The number of spikes (expressed as % of control) during voiding bladder contractions was significantly and dose-dependently decreased by intrathecal application of muscimol (0.01–0.1 μg) or baclofen (0.01–1 μg). B: The maximal voltage of spikes during voiding bladder contractions was significantly decreased after intrathecal application of muscimol (0.1 μg) or baclofen (1 μg). C: The average voltage of spikes during voiding bladder contractions was significantly decreased after intrathecal application of muscimol (0.1 μg) or baclofen (1 μg). Values are the mean ± standard error (SE). Significant difference from control (Cont): * p < 0.05, and ** p < 0.01.