Table.
Muscimol (n = 8) |
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---|---|---|---|---|---|---|
Control | 0.001 | 0.01 | 0.1 | 1 (μg) | ||
VV (ml) | 0.60 ± 0.17 | 0.53 ± 0.16 | 0.43 ± 0.16 | 0.20 ± 0.06* | – | |
RV (ml) | 0.54 ± 0.21 | 0.63 ± 0.30 | 0.65 ± 0.30 | 1.17 ± 0.33 | – | |
BC (ml) | 1.14 ± 0.38 | 1.11 ± 0.42 | 1.08 ± 0.34 | 1.37 ± 0.35 | – | |
VE (%) | 56.4 ± 5.4 | 50.9 ± 8.0 | 44.2 ± 9.5 | 15.2 ± 4.0** | – | |
Baclofen (n = 8) |
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Control | 0.001 | 0.01 | 0.1 | 1 (μg) | ||
| ||||||
VV (ml) | 0.60 ± 0.14 | 0.53 ± 0.15 | 0.60 ± 0.15 | 0.52 ± 0.19 | 0.24 ± 0.04* | |
RV (ml) | 0.25 ± 0.05 | 0.21 ± 0.03 | 0.28 ± 0.07 | 0.29 ± 0.08 | 0.61 ± 0.25 | |
BC (ml) | 0.85 ± 0.15 | 0.74 ± 0.15 | 0.88 ± 0.15 | 0.81 ± 0.20 | 0.86 ± 0.25 | |
VE (%) | 66.1 ± 7.7 | 65.4 ± 7.9 | 67.0 ± 9.4 | 59.9 ± 7.7 | 40.6 ± 11.3* |
Values are the mean ± SE. Significant differences when compared with before application (control) are indicated by:
p < 0.05 and
p < 0.01.
VV: voided volume, RV: residual volume, BC: bladder capacity, VE: voiding efficiency