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. Author manuscript; available in PMC: 2009 Sep 15.
Published in final edited form as: J Urol. 2008 Mar;179(3):1178–1183. doi: 10.1016/j.juro.2007.10.030

Table.

The Effects of intrathecal application of muscimol and baclofen in cystometric parameters in SCI rats

Muscimol (n = 8)
Control 0.001 0.01 0.1 1 (μg)
VV (ml) 0.60 ± 0.17 0.53 ± 0.16 0.43 ± 0.16 0.20 ± 0.06*
RV (ml) 0.54 ± 0.21 0.63 ± 0.30 0.65 ± 0.30 1.17 ± 0.33
BC (ml) 1.14 ± 0.38 1.11 ± 0.42 1.08 ± 0.34 1.37 ± 0.35
VE (%) 56.4 ± 5.4 50.9 ± 8.0 44.2 ± 9.5 15.2 ± 4.0**
Baclofen (n = 8)
Control 0.001 0.01 0.1 1 (μg)

VV (ml) 0.60 ± 0.14 0.53 ± 0.15 0.60 ± 0.15 0.52 ± 0.19 0.24 ± 0.04*
RV (ml) 0.25 ± 0.05 0.21 ± 0.03 0.28 ± 0.07 0.29 ± 0.08 0.61 ± 0.25
BC (ml) 0.85 ± 0.15 0.74 ± 0.15 0.88 ± 0.15 0.81 ± 0.20 0.86 ± 0.25
VE (%) 66.1 ± 7.7 65.4 ± 7.9 67.0 ± 9.4 59.9 ± 7.7 40.6 ± 11.3*

Values are the mean ± SE. Significant differences when compared with before application (control) are indicated by:

*

p < 0.05 and

**

p < 0.01.

VV: voided volume, RV: residual volume, BC: bladder capacity, VE: voiding efficiency