Table 1.
Comparisons between participants with and without erosive esophagitis (n = 5037)
| With erosive esophagitis (n = 1679) | Without erosive esophagitis (n = 3358) | P | |
| Age (yr, mean ± SD) | 45.2 ± 9.3 | 45.2 ± 9.7 | 0.873 |
| Gender (M/F, %) | 86/14 | 59/41 | < 0.001 |
| BMI (kg/m2) | 24.8 ± 2.9 | 23.5 ± 3.0 | < 0.001 |
| Waist circumference (cm) | 86.8 ± 8.7 | 81.5 ± 9.8 | < 0.001 |
| Current smoking | 724 (43%) | 786 (23%) | < 0.001 |
| Alcohol use (≥ 3-4/wk) | 360 (21%) | 387 (12%) | < 0.001 |
| Metabolic syndrome | 352 (21%) | 433 (13%) | < 0.001 |
| Hiatal hernia | 38 (2.2%) | 24 (0.7%) | < 0.001 |
| Reflux symptoms1 | 194 (12%) | 265 (8.0%) | < 0.001 |
| Systolic BP (mmHg) | 118.3 ± 12.7 | 114.8 ± 13.5 | < 0.001 |
| Diastolic BP (mmHg) | 77.7 ± 8.8 | 74.8 ± 9.5 | < 0.001 |
| Fatty liver on abdominal USG | 809 (48%) | 1014 30%) | < 0.001 |
| Fasting plasma glucose | 98.4 ± 20.5 | 95.2 ± 17.2 | < 0.001 |
| HbAlc | 5.6 ± 0.7 | 5.5 ± 0.6 | 0.001 |
| Triglycerides (mg/dL, mean ± SD) | 158.9 ± 110.4 | 123.5 ± 78.6 | < 0.001 |
| HDL-C (mg/dL) (mean ± SD) | 54.1 ± 12.0 | 56.4 ± 12.8 | < 0.001 |
| HOMA2 | 2.41 ± 1.10 | 2.18 ± 0.89 | < 0.001 |
| H pylori positive | 211/555 (38%) | 498/922 (54%) | < 0.001 |
| Education (college and higher) | 894/1184 (75%) | 1639/2391 (69%) | < 0.001 |
1
Reflux symptoms: Weekly heartburn and/or acid regurgitation;
2
HOMA: Homeostasis model assessment estimates steady state beta cell function and insulin sensitivity.