Table 1.
Relationship between TS and clinicopathological characteristics of ESCC
| Factor | n | (+) | (-) | Positive (%) | P value |
| Sex | |||||
| M | 86 | 40 | 46 | 46.51 | |
| F | 16 | 3 | 13 | 18.75 | 0.039 |
| Age (yr) | |||||
| < 60 | 58 | 27 | 31 | 46.55 | |
| ≥ 60 | 44 | 16 | 28 | 36.36 | 0.302 |
| Histological grade | |||||
| Well | 32 | 7 | 25 | 21.88 | |
| Moderate & poor | 70 | 36 | 34 | 51.43 | 0.005 |
| Lymph node metastasis | |||||
| (-) | 55 | 24 | 31 | 43.64 | |
| (+) | 47 | 19 | 28 | 40.43 | 0.743 |
| Location1 | |||||
| Upper | 11 | 4 | 7 | 36.36 | |
| Middle | 55 | 22 | 33 | 40.00 | |
| Lower | 36 | 17 | 19 | 47.22 | 0.822 |
| T Stage | |||||
| T0-1 | 7 | 4 | 3 | 57.14 | |
| T2-4 | 95 | 39 | 56 | 41.04 | 0.405 |
1
Location: Upper, upper intra-thoracic esophagus; Middle, middle intra-thoracic esophagus; Lower, lower intra-thoracic esophagus. TS: Thymidylate synthase; ESCC: Esophageal squamous cell carcinoma.