Table 1.
Clinical Characteristics of Genetically Screened Patients With Non–Small-Cell Lung Cancer
| Characteristic | Patients (N = 141) |
|
|---|---|---|
| No. | % | |
| Age, years | ||
| Median | 63 | |
| Range | 29-90 | |
| Sex | ||
| Male | 48 | 34 |
| Female | 93 | 66 |
| Smoking history† | ||
| Never smoker | 59 | 42 |
| Light smoker | 26 | 18 |
| Smoker | 56 | 40 |
| Ethnicity | ||
| Asian | 9 | 6 |
| Non-Asian | 132 | 94 |
| Pathology | ||
| Adeno | 89 | 63 |
| BAC* | 41 | 29 |
| Adenosquamous | 4 | 3 |
| Squamous | 2 | 1 |
| Large cell/NOS | 5 | 4 |
| Stage‡ | ||
| IA | 14 | 10 |
| IB | 11 | 8 |
| IIA | 1 | 1 |
| IIB | 0 | 0 |
| IIIA | 5 | 4 |
| IIIB | 4 | 3 |
| IV | 96 | 68 |
| Multifocal BAC | 10 | 7 |
Abbreviations: adeno, adenocarcinoma; BAC, bronchioloalveolar carcinoma; NOS, not otherwise specified.
*
Adenocarcinoma with any element of BAC was listed as BAC.
†
Never smokers have smoked < 100 cigarettes in their lifetime; light smokers have smoked ≤ 10 pack years; and smokers have smoked > 10 pack years.
‡
Clinical stage represents stage at time of mutation testing. Stage was determined according to current American Joint Commission on Cancer guidelines; however, patients with malignant pleural effusions were classified as stage IV.