Table A1.
Clinical Characteristics of Patients With WT/WT Genotype According to KRAS Mutation Status
| Characteristic |
KRAS Status |
P | |||||
|---|---|---|---|---|---|---|---|
| MUT (n = 6) |
WT (n = 17) |
ND (n = 68) |
|||||
| No. | % | No. | % | No. | % | ||
| Age, years | .046 | ||||||
| Median | 72 | 51 | 65 | ||||
| Range | 39-83 | 29-83 | 41-87 | ||||
| Sex | .660 | ||||||
| Male | 2 | 33 | 8 | 47 | 19 | 28 | |
| Female | 4 | 67 | 9 | 53 | 49 | 72 | |
| Smoking history | .843 | ||||||
| Never smoker | 1 | 17 | 6 | 35 | 17 | 25 | |
| Light smoker | 2 | 33 | 5 | 29 | 8 | 12 | |
| Smoker | 3 | 50 | 6 | 35 | 43 | 63 | |
| Ethnicity | 1.000 | ||||||
| Asian | 0 | 0 | 2 | 12 | 5 | 7 | |
| Non-Asian | 6 | 100 | 15 | 88 | 63 | 93 | |
| Pathology | 1.000* | ||||||
| Adeno | 4 | 67 | 12 | 71 | 33 | 49 | |
| BAC | 1 | 17 | 2 | 12 | 29 | 43 | |
| Adenosquamous | 0 | 0 | 1 | 6 | 2 | 3 | |
| Squamous | 0 | 0 | 1 | 6 | 1 | 1 | |
| Large cell/NOS | 1 | 17 | 1 | 6 | 3 | 4 | |
| Stage | 1.000† | ||||||
| IA | 0 | 0 | 1 | 6 | 9 | 13 | |
| IB | 0 | 0 | 0 | 0 | 10 | 15 | |
| IIA | 0 | 0 | 0 | 0 | 1 | 1 | |
| IIB | 0 | 0 | 0 | 0 | 0 | 0 | |
| IIIA | 0 | 0 | 1 | 6 | 2 | 3 | |
| IIIB | 1 | 17 | 1 | 6 | 2 | 3 | |
| IV | 4 | 67 | 14 | 82 | 35 | 51 | |
| Multifocal BAC | 1 | 17 | 0 | 0 | 9 | 13 | |
Abbreviations: MUT, mutation; WT, wild type; ND, not determined; adeno, adenocarcinoma; BAC, bronchioloalveolar carcinoma; NOS, not otherwise specified.
*
Adeno and BAC v all others.
†
Stages I to III v IV.