Table 1.
Characteristics of the Study Population and Bivariate Associations With All-Cause Mortality
| Characteristic | Study Participants (N = 496) |
Association With All-Cause Mortality |
P | ||
|---|---|---|---|---|---|
| No. | % | Unadjusted Hazard Ratio | 95% CI | ||
| Status | |||||
| Alive | 163 | 32.9 | |||
| Dead | 333 | 67.1 | |||
| Cause of death (n = 333) | |||||
| Colon cancer | 219 | 65.8 | |||
| Other | 114 | 34.2 | |||
| Median follow-up time, months | 58.2 | ||||
| Age, years | 1.25* | 1.14 to 1.37 | |||
| Mean | 66.9 | ||||
| Standard deviation | 12.2 | ||||
| Sex | |||||
| Male | 225 | 45.4 | Ref | ||
| Female | 271 | 54.6 | 1.08 | 0.87 to 1.34 | |
| Race | |||||
| White | 303 | 61.2 | Ref | ||
| African American | 193 | 38.9 | 1.23 | 0.99 to 1.53 | |
| Time of surgery | .08 | ||||
| 1981-1986 | 76 | 15.3 | Ref | ||
| 1987-1991 | 96 | 19.4 | 0.67 | 0.48 to 0.94 | |
| 1992-1996 | 133 | 26.8 | 0.69 | 0.50 to 0.95 | |
| 1997-2002 | 191 | 38.5 | 0.75 | 0.55 to 1.02 | |
| Private insurance | |||||
| Yes | 334 | 67.6 | Ref | ||
| No | 160 | 32.4 | 1.26 | 1.01 to 1.58 | |
| Smoking status | .77 | ||||
| No | 297 | 59.9 | Ref | ||
| Former | 117 | 23.6 | 0.91 | 0.69 to 1.19 | |
| Current | 82 | 16.5 | 0.98 | 0.73 to 1.32 | |
| ACE-27 comorbidity | < .001 | ||||
| None | 98 | 19.8 | Ref | ||
| Mild | 184 | 37.1 | 0.81 | 0.60 to 1.11 | |
| Moderate | 128 | 25.8 | 1.20 | 0.87 to 1.66 | |
| Severe | 86 | 17.3 | 1.56 | 1.11 to 2.20 | |
| CCI score | .003 | ||||
| 0 | 252 | 50.8 | Ref | ||
| 1 | 133 | 26.8 | 1.01 | 0.78 to 1.32 | |
| ≥ 2 | 111 | 22.4 | 1.58 | 1.21 to 2.05 | |
| NIA/NCI comorbidities | .02 | ||||
| 0-1 | 150 | 30.2 | Ref | ||
| 2-3 | 189 | 38.1 | 0.85 | 0.65 to 1.11 | |
| 4-5 | 113 | 22.8 | 1.00 | 0.74 to 1.35 | |
| ≥ 6 | 44 | 8.9 | 1.56 | 1.06 to 2.29 | |
| Tumor stage | < .001 | ||||
| I | 91 | 18.4 | Ref | ||
| II | 169 | 34.1 | 1.43 | 1.00 to 2.05 | |
| II | 137 | 27.6 | 2.48 | 1.72 to 3.58 | |
| IV | 99 | 20.0 | 9.37 | 6.40 to 13.71 | |
| Tumor grade | |||||
| Low | 398 | 80.2 | Ref | ||
| High | 98 | 19.8 | 1.70 | 1.32 to 2.20 | |
| Chemotherapy | |||||
| No | 362 | 73.0 | Ref | ||
| Yes | 134 | 27.0 | 1.74 | 1.38 to 2.20 | |
| BMI | < .01 | ||||
| Underweight | 24 | 4.8 | 1.81 | 1.15 to 2.83 | |
| Normal | 199 | 40.1 | Ref | ||
| Overweight | 168 | 33.9 | 0.86 | 0.67 to 1.11 | |
| Obese | 105 | 21.2 | 0.77 | 0.57 to 1.03 | |
| Recent weight loss | |||||
| No | 336 | 67.7 | Ref | ||
| Yes | 160 | 32.3 | 1.52 | 1.22 to 1.90 | |
| Obstruction | |||||
| No | 349 | 70.4 | Ref | ||
| Yes | 147 | 29.6 | 1.98 | 1.58 to 2.48 | |
| Received blood | |||||
| No | 471 | 95.0 | Ref | ||
| Yes | 25 | 5.0 | 1.96 | 1.26 to 3.06 | |
Abbreviations: Ref, referent; ACE-27, Adult Comorbidity Evaluation-27; CCI, Charlson Comorbidity Index; NIA/NCI, National Institute on Aging and National Cancer Institute; BMI, body mass index.
*
For each 10-year increase in age.