Table 2.
Association of Comorbidity Indices With Mortality
| Variable | ACE-27 |
NIA/NCI Index |
CCI |
|||
|---|---|---|---|---|---|---|
| Adjusted* HR | 95% CI | Adjusted* HR | 95% CI | Adjusted* HR | 95% CI | |
| Comorbidity level | ||||||
| Not severe,† < 6,‡ < 2§ | Ref | Ref | Ref | |||
| Severe,† ≥ 6,‡ or ≥ 2§ | 1.63 | 1.24 to 2.15 | 1.83 | 1.29 to 2.61 | 1.46 | 1.14 to 1.88 |
| Race | ||||||
| White | Ref | Ref | Ref | |||
| African American | 1.34 | 1.06 to 1.68 | 1.34 | 1.07 to 1.69 | 1.36 | 1.08 to 1.71 |
| Stage | ||||||
| I-II | Ref | Ref | Ref | |||
| III | 1.95 | 1.50 to 2.54 | 2.06 | 1.57 to 2.69 | 1.95 | 1.49 to 2.54 |
| IV | 8.96 | 6.60 to 12.18 | 8.66 | 6.39 to 11.73 | 8.54 | 6.30 to 11.57 |
| Grade | ||||||
| Low | Ref | Ref | Ref | |||
| High | 1.55 | 1.19 to 2.03 | 1.66 | 1.27 to 2.16 | 1.59 | 1.22 to 2.08 |
| BMI | ||||||
| Underweight | 1.54 | 0.96 to 2.45 | 1.56 | 0.98 to 2.49 | 1.54 | 0.97 to 2.46 |
| Normal | Ref | Ref | Ref | |||
| Overweight/obese | 0.77 | 0.61 to 0.97 | 0.80 | 0.63 to 1.00 | 0.77 | 0.61 to 0.97 |
| Bowel obstruction | 1.51 | 1.19 to 1.91 | 1.54 | 1.21 to 1.94 | 1.52 | 1.20 to 1.93 |
Abbreviations: ACE-27, Adult Comorbidity Evaluation-27; NIA/NCI, National Institute on Aging and National Cancer Institute; CCI, Charlson Comorbidity Index; HR, hazard ratio; Ref, referent; BMI, body mass index.
*
Adjusted for the variables listed as well as age.
†
According to ACE-27.
‡
According to NIA/NCI index.
§
According to CCI.