Figure 2. Severity of ARF for the three age groups, as assessed by BUN concentrations.
With each of 3 ARF models, the severity of renal dysfunction increased with advancing age. The p values compare the youngest vs. the oldest groups, whereas the r values reflect the overall correlation coefficients between individual body wts and BUN concentrations for each ARF model (n, 6-10 mice per group). Baseline BUN concentrations were 25±2 mg/dL and did not significantly differ between the groups.
