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. Author manuscript; available in PMC: 2009 Sep 15.
Published in final edited form as: Kidney Int. 2008 Jun 18;74(5):674–678. doi: 10.1038/ki.2008.251

Figure 4. Effects of increasing maleate and glycerol dosages in ‘juvenile’ mice on the severity of ARF.

Figure 4

Left panel: Increasing maleate from 600 to 800 mg/Kg failed to induce azotemia in ‘juvenile’ mice. At 1000 mg/Kg, toxicity was apparent, but it was significantly less than that observed in ‘mature’ mice at a 600 mg/Kg maleate dosage. Right panel: Increasing glycerol dosage from 9 to 12 mg/Kg in ‘juvenile’ mice induced azotemia, but it was significantly less than that observed in ‘mature’ mice (n, 5-10 / group).