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. Author manuscript; available in PMC: 2009 Sep 15.
Published in final edited form as: Kidney Int. 2008 Jun 18;74(5):674–678. doi: 10.1038/ki.2008.251

Figure 7. RNA polymerase II (Pol II) density at target gene loci, as assessed by matrix ChIP assay (ref. 30).

Figure 7

Pol II was assessed at the start (exon 1) and end exons of the HMGCR and LDL-R genes. The ‘juvenile’ mice had higher Pol II densities at both HMGCR exons (#1, #19) and both LDL-R exons (#1, #18), compared to the ‘mature’ mice. These results exactly paralleled the directional changes seen in their cognate mRNAs (n, 6 determinations per group).