Figure 8. Pol II, SREBP-1, and SREBP-2 at the HMGCR promoter region in ‘juvenile’ and ‘mature’ mice.
Pol II was measured at two sites within the promoter (-100 and -400 base pairs, bp, from 5′ to transcription start site, TSS), whereas the SREBPs were measured only at the -100 bp region. The amount of Pol II and both SREBPs were ∼2-3× higher in the younger mouse kidneys (n, 6 for each).
