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. Author manuscript; available in PMC: 2010 Feb 1.

Published in final edited form as: Circ Cardiovasc Genet. 2009 Jan 23;2(1):38–45. doi: 10.1161/CIRCGENETICS.108.817064

Table 5.

Association of Selected Haplotypes With BP

				Systolic BP			Diastolic BP
Haplotype Serial No.	^* SNP	Haplotype	Frequency%,	χ²	Observed P	Empirical P^†	χ²	Observed P	Empirical P^†
Hap1-4	rs2315314	G-T-G-C-C-G	13.6	14.17	0.00020	0.00820	15.82	0.00007	0.00240
Hap2-3	rs7744171	A-C-A	16.8	2.89	0.08930	0.84543	12.12	0.00050	0.01460
Hap3-1	rs13237260	A-A-G	48.4	10.97	0.00090	0.02260	7.54	0.00600	0.13137
Hap3-2	rs13237260	G-A-T	37.1	11.94	0.00050	0.01420	7.34	0.00680	0.14537
Hap4-2	rs7804315	T-C-A-A	33.5	8.23	0.00410	0.10458	11.93	0.00060	0.01880
Hap5-3	rs12673992	A-C-T	24.3	7.99	0.00470	0.10098	11.96	0.00050	0.01460
Hap6-2	rs2160010	T-C-G-G	27.2	10.22	0.00140	0.03579	17.22	0.00003	0.00160

^*

BP-associated SNP residing on haplotype.

^†

Based on 5000 permutations, this accounts for multiple comparisons within each phenotype.